Multipette® M4 - Multi-Dispenser Pipette

The Multipette<sup>&reg;</sup> M4 multi-dispenser (repeater pipette) helps you perform long, repetitive pipetting tasks with ease
The Multipette&nbsp;M4<sup>&reg;</sup> multi-dispenser with advanced interface and sensor
Side view of the Multipette<sup>&reg;</sup> M4 multi-dispenser pipette from Eppendorf
The range of Combitips<sup>&reg;</sup> advanced dispenser tips offer a wide spectrum of possibilities
Multipette<sup>&reg;</sup> M4 multi-dispenser with an assortment of fitting Combitips<sup>&reg;</sup> advanced positive displacement pipette tips
Store your Multipette<sup>&reg;</sup>&nbsp;M4 multi-dispenser securely on a Pipette Carousel 2 or Charger Carousel 2 by Eppendorf
Pipette Holder 2 for Multipette<sup>&reg;</sup> M4 multi-dispenser pipette from Eppendorf
Multipette<sup>&reg;</sup>&nbsp;M4 Multi-Dispenser Held By Scientist (Product Close-Up)
Female and Male Scientists Working with Multipette<sup>&reg;</sup>&nbsp;M4 and Eppendorf Conical Tubes
ACT label of sustainability certification for Multipette<sup>&reg;</sup> M4 starter kit
The Multipette<sup>&reg;</sup> M4 multi-dispenser (repeater pipette) helps you perform long, repetitive pipetting tasks with ease
The Multipette&nbsp;M4<sup>&reg;</sup> multi-dispenser with advanced interface and sensor
Side view of the Multipette<sup>&reg;</sup> M4 multi-dispenser pipette from Eppendorf
The range of Combitips<sup>&reg;</sup> advanced dispenser tips offer a wide spectrum of possibilities
Multipette<sup>&reg;</sup> M4 multi-dispenser with an assortment of fitting Combitips<sup>&reg;</sup> advanced positive displacement pipette tips
Store your Multipette<sup>&reg;</sup>&nbsp;M4 multi-dispenser securely on a Pipette Carousel 2 or Charger Carousel 2 by Eppendorf
Pipette Holder 2 for Multipette<sup>&reg;</sup> M4 multi-dispenser pipette from Eppendorf
Multipette<sup>&reg;</sup>&nbsp;M4 Multi-Dispenser Held By Scientist (Product Close-Up)
Female and Male Scientists Working with Multipette<sup>&reg;</sup>&nbsp;M4 and Eppendorf Conical Tubes
ACT label of sustainability certification for Multipette<sup>&reg;</sup> M4 starter kit
Multipette® M4
Multipette® M4

Say goodbye to tedious, time-consuming serial pipetting! The Multipette M4 pipette from Eppendorf is ideal for repetitive dispensing tasks in long series, eliminating the need for repeated liquid aspiration. Paired with Combitips® advanced dispenser tips, the Multipette effortlessly handles viscous, volatile or foaming liquids that pose challenges to traditional pipettes. The hermetically sealed tips in the Multipette/Combitips positive displacement pipetting system ensure a high level of safety when working with infectious, toxic, or radioactive liquids. More information

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Designed according to the Eppendorf PhysioCare Concept<sup>&reg;</sup> for optimal ergonomics
Logo of International non-profit organization My Green Lab for sustainable lab products
Reddot design award 2013 small
Multipette<sup>&reg;</sup> M4 - SelectScience&copy; Scientists' Choice Awards winner, 2015
Order Info

Product Information

Aspirate liquid once and dispense up to 100 times without tip refill


The Multipette M4 mechanical multi-dispenser pipette allows you to aspirate liquid once and dispense up to 100 times, making it the ideal precision instrument for long, repetitive pipetting tasks, such as tube or plate filling, and aliquoting reagents. Liquid is aspirated and dispensed by positive displacement, which means there is no air cushion that may be affected by liquid sample properties. This ensures that the correct volume is always dispensed - regardless of the density, viscosity and volatility of the liquid.

The matching Combitips® advanced and ViscoTip® positive displacement dispenser tips are automatically recognized - eliminating time consuming volume calculations - and are hermetically sealed to provide a high level of user, instrument and sample safety. Ideal for handling infectious, toxic or radioactive liquids.

Eppendorf pioneered the Multipette/Combitips multi-dispenser system in 1978 and improved it several times since. It was the very first pipetting system allowing users to fill the tip once and dispense multiple times. The concept remains a driver for efficient liquid handling and a staple in many labs working with plates or series of tubes. In 2024, our Multipette M4 multi-dispenser was awarded the ACT® Environmental Impact Factor Label along with Combitips advanced dispenser tips, showcasing our dedication to eco-conscious manufacturing and assisting customers in taking environmentally informed purchase decisions.

A repetitive pipette with advanced interface and sensor control for easy operation



Step counter
› Displays the number of executed dispensing steps

Volume selection dial
› 20 different volume settings for every size of Combitips advanced

Motion sensor
Even if a Combitips advanced dispenser tip is left attached, the Multipette M4 switches off when not in use to save power. When moved again, it switches back on automatically, while still “remembering” the number of executed dispensing steps for increased efficiency.

Combitips advanced attachment sensor
› Automatic Combitips advanced tip recognition and volume display
› Ensures a secure connection between Combitips advanced and Multipette M4

Multipette® M4

Make laborious, time-consuming serial pipetting tasks more comfortable


With its easy-to-reach and easily adjustable volume selection dial, the Multipette M4 makes repetitive pipetting tasks manageable. A hand rest supports a relaxed, ergonomic hand position and ease-of-use, ensuring the Multipette M4 provides a greater level of comfort over the day.

The ergonomically shaped operating lever both fills and dispenses the liquid, and also ejects the Combitips advanced dispenser tips, with one-handed operation.

Multipette® M4

Convenient storage options for your multi-dispenser & pipettes


Our Multipette M4 pipette holders for wall mounting or the Eppendorf Pipette Holder System can be affixed to virtually any surface or integrated with either our charging or non-charging manual pipette carousel stands. Alternatively, one Multipette M4 multi-dispenser can be stored in the Pipette Stand 2 by Eppendorf.

Multipette® M4

Disposal of packaging and the dispenser at the end of its lifecycle


The packaging of Multipette M4 dispensers contains different materials, including cardboard and plastic foil. Our Multipette packaging cardboard material consists of approx. 92 % recycling material. Please support the global sustainability initiative of recycling valuable raw material by collecting the cardboard and disposing of it in the appropriate collection container at your organization. In respect to the wrapping foils made of LD-PE, we recommend to select a dedicated recycling partner where PE material can be recycled.

Eppendorf liquid handling instruments are designed for many years of use – should the need arise to dispose of your Multipette however, please note that it may potentially be contaminated and includes electronic components and a battery. Please contact your local biosafety officer and/or your local waste management for requirements and best practices concerning electronic and lab waste. You may use the Eppendorf Decontamination Certificate as guidance regarding possible documentation requirements.

Multipette® M4

Features

  • Mechanical positive displacement multi-dispenser: fill the tip once and dispense up to 100 times without a refill
  • Automatic Combitips® advanced dispenser tip recognition eliminates time-consuming volume calculations
  • Easy-to-read display guarantees stress-free and intuitive operation with a digital display of the dispensing volume
  • Wide dispensing range: 1 µL to 10 mL for flexible operation
  • Stress-free work via integrated step counter: dispensing procedures can be continued error free after an interruption or distraction
  • Integrated »Sleep« function switches the instrument off, when it is not being used, thus reducing energy consumption
  • Fully emptied Combitips® advanced tip can be easily ejected with one hand using the operating lever
  • Positive displacement principle: Ideal for viscous or foaming solutions and liquids with high vapor pressure
  • Safe handling of toxic, radioactive or infectious liquids
  • Eco-conscious production: Multipette M4 and Combitips® advanced tips are ACT®-labeled to help you make an informed choice when it comes to sustainability

Applications

  • Repetitive dispensing of volumes in long series such as tube or plate filling, aliquoting reagents and kit usage
  • Safe dispensing of toxic, radioactive and other hazardous liquids
  • Precise and accurate dispensing of viscous solutions (e.g. glycerol) or liquids with high vapor pressure (e.g. ethanol)
 Multipette® M4 Starter Kit - 4982000314Multipette® M4 - 4982000012
Adjustable cone spacingnono
Operating mode  
ACT labelyesyes
Product typeDispensersDispensers
Pipetting typePositive displacement systemPositive displacement system
Channel type1-channel1-channel
Volume range1 µL – 10 mL1 µL – 10 mL
Random measurement errorsee Combitips advancedsee Combitips advanced
Systematic measurement errorsee Combitips advancedsee Combitips advanced
Autoclavablenono
Battery typeButton cellButton cell
ConsumablesCombitips® advanced, ViscoTip®Combitips® advanced, ViscoTip®
Open system (third party consumables)nono
Delivery contentMulti-Dispenser, Battery (inserted), Operating manual, Certificate, Combitips® advanced Box 2.0, Combitips® advanced assortment pack (1 tip of each size), Pipette Holder 2Multi-Dispenser, Battery (inserted), Operating manual, Certificate, Combitips advanced tip 2.5 mL, Pipette Holder 2
Multipette® M4
Video: Multipette® M4 – Multipette® M4 : Key Features
Multipette® M4
Video: Multipette® M4 – How to Pipette Challenging Liquids

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